Frizzled related protein deficiency impairs muscle strength, gait and calpain 3 levels

Limb-girdle muscular dystrophy recessive 1 calpain3-related (LGMDR1), previously known as LGMD2A, is a disease caused by mutations in the CAPN3 gene. It is characterized by progressive weakness and muscle degener...

Source: Orphanet Journal of Rare Diseases - May 24, 2020 Category: Internal Medicine Authors: Leire Casas-Fraile, Frederique M. Cornelis, Domiziana Costamagna, Anabel Rico, Robin Duelen, Maurilio M. Sampaolesi, Adolfo L ópez de Munain, Rik J. Lories and Amets Sáenz Tags: Research Source Type: research