Early-life lactoferrin intervention modulates the colonic microbiota, colonic microbial metabolites and intestinal function in suckling piglets.

This study reports the effects of early-life lactoferrin (LF) intervention on the colonic microbiota, intestinal function and mucosal immunity in suckling piglets. A total of 60 Duroc × Landrace × Yorkshire suckling piglets from six sows were assigned to the control (CON) and LF groups in litters. The LF group piglets were fed 0.5 g/kg body weight of LF solution per day, and the CON group piglets were fed the same dose of physiological saline for a week. Six piglets from the two groups were randomly chosen and euthanised on days 8 and 21. The LF group piglets had higher ACE and Chao1 indices of colonic microbiota than the CON group piglets (P 
Source: Applied Microbiology and Biotechnology - Category: Microbiology Authors: Tags: Appl Microbiol Biotechnol Source Type: research

Related Links:

CONCLUSIONS: In summary, microbial EVs demonstrated the potential in their use as novel biomarkers for AD diagnosis. Therefore, future work should investigate larger case and control groups with cross-sectional or longitudinal clinical data to explore the utility and validity of serum microbiota EV-based AD diagnosis. PMID: 32638560 [PubMed]
Source: Allergy, Asthma and Immunology Research - Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research
This study highlights the importance of IS to the evolution ofShigella and provides a framework for the investigation of IS dynamics and metabolic reduction in other bacterial species.
Source: PLoS Genetics - Category: Genetics & Stem Cells Authors: Source Type: research
Previous studies have identified oral administration of antibiotics and gut-impacting drugs as critical drivers for fecal antibiotic resistance (AR) and microbiome disruption in lab mice, but the practical implications of these findings have yet to be validated in hosts nurtured in conventional environment. Using ampicillin (Amp) as a way to extrapolate the general effect of antibiotics, this project examined the impact of drug administration routes on fecal microbiota and resistome using poultry raised in a teaching farm. AR genes were found to be abundant in the feces of young Leghorn chicks without previous antibiotic t...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Abstract Chitosan is a biopolymer discovered abundantly on earth specifically in the exoskeleton of shrimps, crabs and insects. In the present study, isolation and characterization of chitosan from the pen shell Pinna bicolor was carried out. In addition to this, the chitosan acquired from the pen shell was tested for its antibacterial activity against five bacterial strains. The FTIR analysis confirmed the presence of NH out of plane bending (872 cm-1) and C-O-C stretching (1016 cm-1) for chitosan with 59.76% degree of deacetylation. The Micro Raman showed peaks at 1658 cm-1, 1595 cm-1 and at 954 cm-1 c...
Source: International Journal of Biological Macromolecules - Category: Biochemistry Authors: Tags: Int J Biol Macromol Source Type: research
Abstract Current studies have indicated association of gut microbiome composition with varieties of disorders including infectious diseases. The microbiome composition is different among races and countries, possibly resulting in diversified interaction between host immune and gut microbiome. Characterization of the baseline microbiota in healthy people is an essential step to understand this biological interaction in individual populations. However, data on gut/fecal microbiome has not been accumulated in West Africa. In the present study, we examined fecal microbiome composition in healthy adults in Ghana. The 1...
Source: Japanese Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Jpn J Infect Dis Source Type: research
ConclusionOur study demonstrates that the DSA for Shigella isolates was severe, and the plasmid-mediated mphA gene was the most common macrolide resistance gene detected in Shigella isolates collected in Anhui, China. The mphA-positive S. flexneri isolates with high-level DSA facilitated clonal spread in children and the elderly. This finding is noteworthy and warrants further study.
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
CONCLUSIONS Patients with stage 5 CKD on a very low-protein diet showed changes in the intestinal microbiota that could be transferred from humans to rats by fecal microbiota transplantation. PMID: 32592577 [PubMed - as supplied by publisher]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
Journal of Agricultural and Food ChemistryDOI: 10.1021/acs.jafc.0c01901
Source: Journal of Agricultural and Food Chemistry - Category: Food Science Authors: Source Type: research
This report highlights three examples of outbreaks that occurred during 2018-2019, were caused by leading etiologies (Shigella, norovirus, or STEC), and demonstrate the wide geographic distribution of such outbreaks across the United States. Detection and investigation of untreated recreational water-associated outbreaks are challenging, and the sources of these outbreaks often are not identified. Tools for controlling and preventing transmission of enteric pathogens through untreated recreational water include epidemiologic investigations, regular monitoring of water quality (i.e., testing for fecal indicator bacteria), m...
Source: MMWR Morb Mortal Wkl... - Category: Epidemiology Authors: Tags: MMWR Morb Mortal Wkly Rep Source Type: research
Authors: Phuyal N, Jha PK, Raturi PP, Rajbhandary S Abstract Crude methanol extracts of fruits, seeds, and bark of Zanthoxylum armatum were investigated in vitro for antimicrobial activities against 9 different bacterial strains: Bacillus subtilis, Enterococcus faecalis, Proteus vulgaris, Pseudomonas aeruginosa, Salmonella typhi, Shigella dysenteriae, Staphylococcus aureus, methicillin-resistant Staphylococcus aureus (MRSA), and Staphylococcus epidermidis using agar well diffusion method, and the MBC values were determined. Only 5 bacteria, i.e., Bacillus subtilis, Enterococcus faecalis, MRSA, Staphylococcus aureus...
Source: Journal of Tropical Medicine - Category: Tropical Medicine Tags: J Trop Med Source Type: research
More News: Biotechnology | Dysentery | Gastroenteritis | Genetics | Microbiology | Study