Surgery versus radical endotherapies for early cancer and high-grade dysplasia in Barrett's oesophagus.

CONCLUSIONS: This Cochrane review has indicated that there are no RCTs to compare management options in this vital area, therefore trials should be undertaken as a matter of urgency. The problems with such randomised methods are standardising surgery and endotherapies in all sites, standardising histopathology in all centres, assessing which patients are fit or unfit for surgery and making sure there are relevant outcomes for the study (i.e. long-term survival (over five or more years)) and no progression of HGD.
PMID: 32442322 [PubMed - as supplied by publisher]

Source: Cochrane Database of Systematic Reviews - May 21, 2020 Category: General Medicine Authors: Bennett C, Green S, DeCaestecker J, Almond M, Barr H, Bhandari P, Ragunath K, Singh R, Jankowski J Tags: Cochrane Database Syst Rev Source Type: research