The use of negative pressure wound therapy increases failure rate in debridement and implant retention for acute prosthetic joint infection.

CONCLUSIONS: The treatment success rate after failed DAIR and NPWT with 36% is low and associated with a high treatment failure rate (permanent girdlestone arthroplasty, fistula or amputation, death). Thus, the definition of risk factors is crucial. We found that the number of revisions until wound consolidation, a polymicrobial PJI and detection of a difficult-to-treat organisms were risk factors for treatment failure. Furthermore, after failed DAIR/NPWT we could detect a significant higher number of different bacterial strains, with a possible adverse effect on a consecutive exchange. PMID: 32444587 [PubMed - as supplied by publisher]
Source: Technology and Health Care - Category: Medical Devices Authors: Tags: Technol Health Care Source Type: research