Benign anorectal conditions: perianal abscess, fistula in ano, haemorrhoids, fissures and pilonidal sinus

This article summarizes the presentation and current management of perianal abscess, fistula in ano, haemorrhoids, fissure and pilonidal sinus.
Source: Surgery (Medicine Publishing) - Category: Surgery Authors: Tags: Intestinal surgery – II Source Type: research

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ConclusionsInjection of botulinum toxin in the anal sphincters is a safe and effective analgesic option in patients with anal fissure while actively receiving chemotherapy.
Source: Supportive Care in Cancer - Category: Cancer & Oncology Source Type: research
CONCLUSION: Detailed analysis of the information collected on S. roxburghii suggested some promising leads for future drug development. However, many scientific gaps were found in the study of this and further extensive investigation is needed to fully understand the mechanism of action of the active constituents and exploit its therapeutic promises. PMID: 32646358 [PubMed - as supplied by publisher]
Source: Mini Reviews in Medicinal Chemistry - Category: Chemistry Authors: Tags: Mini Rev Med Chem Source Type: research
Defective BRCA genes are well known for their ability to cause breast and ovarian cancers in women. But these same gene defects are also strong risk factors for aggressive prostate cancer in men. About 10% of men with metastatic prostate cancer — meaning cancer that is spreading away from the prostate — test positive for genetic mutations in BRCA genes. Fortunately, these cancers can be treated with new types of personalized therapies. In May, the FDA approved two new drugs specifically for men with BRCA-positive metastatic prostate cancer that has stopped responding to other treatments. One of the drugs, calle...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Health Prostate Knowledge Treatments HPK Source Type: blogs
ConclusionsMaximal reduction of the rectal dose seems very important to prevent serious rectal hemorrhage. In addition, we should consider the risk of rectal toxicities in patients with abnormalities in the rectal mucosa, especially hemorrhoids.
Source: International Journal of Clinical Oncology - Category: Cancer & Oncology Source Type: research
THURSDAY, May 28, 2020 -- As the evidence piles up that a malaria drug touted as a possible coronavirus treatment by President Donald Trump may instead harm patients, a new study shows the same might hold true for cancer patients with...
Source: - Daily MedNews - Category: General Medicine Source Type: news
ConclusionsPET/CT scans occasionally showed high FDG uptake in the anal canal of healthy adults. Comparing the SUVmax values of liver FDG uptake may help differentiate between normal tissue and anal cancer.
Source: Annals of Nuclear Medicine - Category: Nuclear Medicine Source Type: research
Like everyone, I assume I’ll live forever. Although I often wonder whether anyone would come to my funeral and who would wear black, it never actually occurrs to me that there is an endpoint. It’s almost as if I would come along too to watch proceedings running smoothly and along the lines I wanted. Death was something I thought about, but in a rather abstract, offhand sort of way. It happened, of course I knew I would die at some point, but that point was somewhere out there … way off from here, where I am now. And then I hit a brick wall. The wall consisted of a tiny little bit of blood coughed up in s...
Source: The Hysterectomy Association - Category: OBGYN Authors: Tags: Emotional Health Happiness Thought for the day Women's Health my story Source Type: news
This study was granted an educational exception by the Institutional Review Board at Walter Reed National Military Medical Center. RESULTS: Forty-three learners participated in this course. Forty-six percent of participants had not participated in any anorectal cases, 26% had participated in 1 to 5 cases, 17% had participated in 6 to 10 cases, 6% had been involved with 11 to15 cases, and 6% had been involved with more than 15 cases. For learners who had no prior experience, 1 to 5 prior cases, or 6 to 10 cases, there were statistically and educationally significant increases in confidence for all diagnoses and procedur...
Source: Military Medicine - Category: International Medicine & Public Health Tags: Mil Med Source Type: research
We often think of self-development as a pursuit that builds positive capabilities such as courage, ambition, or a success mindset. And of course it can generate many positive results if we truly invest in it, such as loving relationships, a meaningful and lucrative career, and a rewarding lifestyle. But we can easily overlook just how beautifully self-development protects us from major problems in life, including serious but common problems that drag many people down for years, if not decades. Preventing Self-Destruction I originally got into self-development as a path away from self-destructive behavior when I wa...
Source: Steve Pavlina's Personal Development Blog - Category: Psychiatry & Psychology Authors: Tags: Health Lifestyle Source Type: blogs
AbstractBackgroundAnal cancer is a relatively rare tumor of which incidence increases in developed countries.18F-FDG PET has been increasingly used for its post radio-chemotherapy evaluation. However, several authors have reported the risk of local false-positive findings leading to low specificity and positive predictive values. These false-positive results could be due to post-radiotherapy inflammation or infection but certainly also to physiological anal canal uptake that is observed on a regular basis in clinical practice. The purpose of this prospective study (NCT03506529; HYPHYCA) was therefore to seek predictive fac...
Source: EJNMMI Research - Category: Radiology Source Type: research
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