Investigation of GHSR methylation levels in thymomas from patients with Myasthenia Gravis.

CONCLUSIONS: GHSR hypermethylation is not a pan-cancer marker or an early event in TAMG, but occurs in almost 1/4 of them and mainly from stage II onward. Subsequent studies are required to clarify the molecular pathways leading to GHSR hypermethylation in TAMG tissues and their relevance to disease progression.
PMID: 32442579 [PubMed - as supplied by publisher]

Source: Gene - May 18, 2020 Category: Genetics & Stem Cells Authors: Coppedè F, Stoccoro A, Nicolì V, Gallo R, De Rosa A, Guida M, Maestri M, Lucchi M, Ricciardi R, Migliore L Tags: Gene Source Type: research