The Effect of Prophylactic Central Neck Dissection During Hemithyroidectomy on Locoregional Recurrence in Patients With Papillary Thyroid Carcinoma: A Meta-Analysis.

CONCLUSION: Prophylactic central neck dissection significantly reduced the risk of recurrence in the central compartment in patients undergoing hemithyroidectomy. PMID: 32434311 [PubMed]
Source: Clinical and Experimental Otorhinolaryngology - Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

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Publication date: Available online 9 July 2020Source: Brazilian Journal of OtorhinolaryngologyAuthor(s): Minxin Wang, Xiaoting Wang, Hongsheng Zhang
Source: Brazilian Journal of Otorhinolaryngology - Category: ENT & OMF Source Type: research
We describe a case of papillary carcinoma in a thyroglossal cyst with left hemiagenesis of the thyroid gland in a 24-year-old female patient. We opted not to perform a total thyroidectomy as the patient was at low risk for aggressive disease. In this article we review the criteria for selection of thyroidectomy in incidentally discovered papillary carcinomas after thyroglossal cyst excision and management protocol in case of coexisting thyroid hemi-agenesis. To our knowledge, this case represents the second case report of an association between left thyroid hemiagenesis and thyroglossal duct cyst papillary carcinoma.
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - Category: ENT & OMF Source Type: research
AbstractBackgroundThe study evaluated the recurrence rate in patients with papillary thyroid carcinoma (PTC) and clinically apparent lymph node metastases (LNM) (cN1) who had low thyroglobulin (Tg) after total thyroidectomy and who were not submitted to adjuvant therapy with131I.MethodsThis was a prospective study. It included 82 cN1 patients ( ≤3 LNM ≤1.5 cm without macroscopic extracapsular extension) with tumors ≤4 cm without macroscopic extrathyroid invasion (T1–2) and who after thyroidectomy had unstimulated Tg (u-Tg) 
Source: Endocrine - Category: Endocrinology Source Type: research
Conditions:   Cardiovascular Disorder;   Chronic Kidney Disease;   Metastatic Renal Cell Carcinoma;   Metastatic Thyroid Gland Medullary Carcinoma;   Stage IV Renal Cell Cancer AJCC v8;   Stage IV Thyroid Gland Medullary Carcinoma AJCC v8;   Stage IVA Thyroid Gland Medullary Carcinoma AJ CC v8;   Stage IVB Thyroid Gland Medullary Carcinoma AJCC v8;   Stage IVC Thyroid Gland Medullary Carcinoma AJCC v8 Interventions:   Other: Best Practice;   Other: Blood Pressure Me...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
CONCLUSIONS: The expression of linc00324 is significantly increased in PTC tissues and cells. Silencing linc00324 may inhibit the proliferation of PTC cells, arrest the cell cycle in G1/G0 phase, and promote the apoptosis by inhibiting the Notch signaling pathway. PMID: 32633374 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Thyroid, Ahead of Print.
Source: Thyroid - Category: Endocrinology Authors: Source Type: research
Conditions:   Thyroid Carcinoma;   Thyroid Cancer;   Thyroid Cancer, Follicular;   Thyroid Cancer (Follicular Cell);   Thyroid Cancer, Papillary;   BRAF V600E Mutation Positive Interventions:   Diagnostic Test: I-124 PET/CT lesion dosimetry;   Drug: Vemurafenib;   Drug: Copanlisib Sponsor:   Memorial Sloan Kettering Cancer Center Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
AbstractObjectiveTo compare the clinical outcome in patients who received adjuvant therapy with radioactive iodine (RAI) using different preparation methods, namely, thyroid hormone withdrawal (THW) and recombinant human thyroid-stimulating hormone (rhTSH), after undergoing thyroidectomy for intermediate- to high-risk differentiated thyroid carcinoma (DTC) according to the American Thyroid Association criteria.MethodsBetween May 2012 and October 2018, 136 patients who underwent adjuvant therapy with high-dose (3700  MBq) RAI for DTC without any metastatic lesions or macroscopic residual lesions after surgical resectio...
Source: Annals of Nuclear Medicine - Category: Nuclear Medicine Source Type: research
[Suspected rare manifestation of a thyroglossal and lateral cervical cyst-a diagnostic and therapeutic approach]. HNO. 2020 Jul 03;: Authors: Karal A, Capraro J, Metternich F, Müller M Abstract A 34-year-old female patient presented to our department with a 1.5 cm midline cystic lesion of the neck. A second cystic mass was found in level 2 of the left lateral neck. Following complete resection, histopathological examination revealed the diagnosis of a dystopic papillary thyroid carcinoma. Total thyroidectomy and bilateral neck dissection were performed. The pat...
Source: HNO - Category: ENT & OMF Tags: HNO Source Type: research
Conclusion: I131 radiotherapy might exert therapeutic effects by targeting CDH5, KDR, CD34, FLT4, EMCN, FLT1, ROBO4, PTPRB, and CD93 in THCA patients. PMID: 32626543 [PubMed - in process]
Source: Disease Markers - Category: Laboratory Medicine Tags: Dis Markers Source Type: research
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