Why attempts to use antiviral drugs to fight COVID-19 are so different from the early days of HIV

Doctors are exploring how to attack COVID-19 with antiviral treatments repurposed from HIV and Ebola.
Source: CBC | Health - Category: Consumer Health News Tags: News/Health Source Type: news

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By Carol Bales , Advocacy and policy communications manager, IntraHealth International ; Casey Bishopp, Communications officer, IntraHealth InternationalMay 22, 2020Here in North Carolina, we all know someone who works in health care. Maybe there’s a nurse in your family, a physician, a data clerk, a pharmacist.These“frontline health workers” are in the spotlight right now as they face unprecedented dangers during every shift they work.Frontline health workers are literally putting themselves on the line—at great personal risk—to respond to COVID-19, stop its spread, and save their patient...
Source: IntraHealth International - Category: International Medicine & Public Health Authors: Tags: Infectious Diseases COVID-19 Advocacy Health Workers Source Type: news
This article is republished from The Conversation under a Creative Commons license. Read the original article. The post Why More Must be Done to Fight Bogus COVID-19 Cure Claims appeared first on Inter Press Service.
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Global Headlines Health Source Type: news
by Jing Wan,Yuqiong Huang, Amaneh Abdel Hafez Aljaafreh, Dandan Dong, Yali Cong , Jun Lin, Hongxiang Chen   COVID-19 is an emerging infectious disease that is extremely contagious and can cause serious consequences and even death. Convalescent plasma, an unregistered therapy, from which the antibodies might suppress the virus, has been proven effective in the treatment of SARS, Ebola and H1N1, without severe adverse events (Chen et al.…
Source: blog.bioethics.net - Category: Medical Ethics Authors: Tags: Clinical Ethics Clinical Trials & Studies Decision making Featured Posts Health Care Informed Consent Research Ethics Social Media #covid19 #diaryofaplagueyear COVID-19 Source Type: blogs
On May 1, the U.S Food and Drug Administration issued an emergency-use authorization of remdesivir, an experimental anti-viral drug. With this clearance, doctors in the U.S. are now allowed to use the drug to treat patients with severe cases of COVID-19. Remdesivir isn’t new. It was initially developed to treat Ebola and was also tested in the lab against SARS and MERS—two other coronaviruses that infect humans much like the virus that causes COVID-19. It never made it to the approval stage for those uses, but over the last four months, scientists desperate for options to help mitigate the coronavirus pandemic ...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 Source Type: news
This study showed that a five-day regimen is as effective as 10 days–that’s important, doctors say, since it could mean shorter stays in the hospital, which could alleviate some of the burden on the health care system. “Of course we will have to wait for the final review of all the data, but it would be very nice to have an anti-viral that’s efficacious in this terrible illness,” says Dr. Aruna Subramanian, a clinical professor of medicine at Stanford and an investigator on the study. “At least we know that we can help patients with this, and that’s really the bottom line.” T...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 feature Magazine Source Type: news
In March 2020, the World Health Organization declared the spread of SARS-CoV-2 a global pandemic. To date, coronavirus disease-2019 (COVID-19) has spread to over 200 countries, leading to over 1.6 million cases and over 99,000 deaths. Given that there is neither a vaccine nor proven treatment for COVID-19, there is currently an urgent need for effective pharmacotherapy. To address the need for an effective treatment of SARS-CoV-2 during the worldwide pandemic, this systematic review of intravenous (IV) remdesivir was performed. Remdesivir, an anti-viral prodrug originally developed to treat Ebola virus disease, has shown b...
Source: Western Journal of Emergency Medicine - Category: Emergency Medicine Source Type: research
From her laboratory in the far western reaches of Montana, Elizabeth Fischer is trying to help people see what they’re up against in COVID-19. Over the past three decades, Fischer, 58, and her team at the Rocky Mountain Laboratories, part of the National Institutes of Health’s (NIH) National Institute of Allergy and Infectious Diseases, have captured and created some of the more dramatic images of the world’s most dangerous pathogens. “I like to get images out there to try to convey that this is an entity, to try to demystify it, so this is something more tangible for people,” says Fischer, on...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 Source Type: news
Authors: Xia J Abstract Recently, an increasing number of reports have indicated that a few patients who were believed to have recovered from COVID-19 initially tested negative but later tested positive. Several hospitals in different countries have detected SARS-CoV-2 RNA in the semen and cerebrospinal fluid of patients with severe COVID-19. Given the fact that the testes and central nervous system are both immune privilege sites and the fact that Ebola virus and Zika virus can avoid immune clearance and continue proliferating and spreading by hiding in those sites, the question of whether SARS-CoV-2 is present in...
Source: BioScience Trends - Category: Biomedical Science Tags: Biosci Trends Source Type: research
Patients lie motionless in a hospital ICU ward, as doctors hurry around their beds. The patients’ faces are concealed by ventilators; the doctors’ by masks. The death rate is rising so quickly that doctors can no longer keep count. “The beds don’t even have time to cool before they are taken up by other patients,” says ICU nurse Cristina Pilati. Yet over the sound of stretchers rolling and monitors beeping, Pilati starts singing the lyrics of ‘Angel’ as she cares for a teenage boy in the ICU. ‘Spend all your time waiting, for that second chance,’ she sings. ‘For a...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 feature Londontime Source Type: news
We describe systems that were put into place during the EVD response in the DRC that can be leveraged for the response to the current COVID-19 global pandemic. PMID: 32431285 [PubMed - as supplied by publisher]
Source: The American Journal of Tropical Medicine and Hygiene - Category: Tropical Medicine Authors: Tags: Am J Trop Med Hyg Source Type: research
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