Pregnant women with COVID-19 show placenta injury in small study

The placentas of 16 pregnant women found to have COVID-19 during routine testing at a Chicago hospital all showed evidence of injury, indicating that women infected with coronavirus may need close monitoring during pregnancy, researchers said on Friday.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news

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AJP Rep 2020; 10: e169-e175 DOI: 10.1055/s-0040-1712925There is a current paucity of information about the obstetric and perinatal outcomes of pregnant novel coronavirus disease 2019 (COVID-19) patients in North America. Data from China suggest that pregnant women with COVID-19 have favorable maternal and neonatal outcomes, with rare cases of critical illness or respiratory compromise. However, we report two cases of pregnant women diagnosed with COVID-19 in the late preterm period admitted to tertiary care hospitals in New York City for respiratory indications. After presenting with mild symptoms, both quickly developed w...
Source: American Journal of Perinatology Reports - Category: Perinatology & Neonatology Authors: Tags: Case Report Source Type: research
Am J Perinatol DOI: 10.1055/s-0040-1712513With the coronavirus disease 2019 (COVID-19) pandemic in the United States, a majority of states have instituted “shelter-in-place” policies effectively quarantining individuals—including pregnant persons—in their homes. Given the concern for COVID-19 acquisition in health care settings, pregnant persons with high-risk pregnancies—such as persons living with HIV (PLHIV)—are increasingly investigating the option of a home birth. Although we strongly recommend hospital birth for PLHIV, we discuss our experience and recommendations for counseling an...
Source: American Journal of Perinatology - Category: Perinatology & Neonatology Authors: Tags: Clinical Opinion Source Type: research
An emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causing coronavirus disease 2019 (COVID-19) pandemic, imposes a great threat to global public health1. The transmission and pathophysiology of SARS-CoV-2 gradually known among various populations, but public health effects of COVID-19 on women and their outcomes should not be ignored1,2. In pregnant and perinatal women, vertical transmission of SARS-CoV-2 from infected mother to her newborn is a controversial issue2-4. SARS-CoV-2 was not detected in vaginal fluid from a women with COVID-195, however, no clear evidence regarding optimal delivery timin...
Source: Journal of Infection - Category: Infectious Diseases Authors: Source Type: research
AbstractIntroductionPrenatal maternal distress has a negative impact on the course of pregnancy, fetal development, offspring development, and later psychopathologies. The study aimed to determine the extent to which the coronavirus disease 2019 (COVID ‐19) pandemic may aggravate the prenatal distress and psychiatric symptomatology of pregnant women.Material and methodsTwo cohorts of pregnant volunteer women were evaluated, one that was recruited before the COVID ‐19 pandemic (n = 496) through advertisements in prenatal clinics in Quebec, Canada, from April 2018 to March 2020; the other (n = 1258) w...
Source: Acta Obstetricia et Gynecologica Scandinavica - Category: OBGYN Authors: Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
We have read with great interest a recent study of Prof. Jin regarding the clinical features and outcomes of pregnant women suspected of 2019 novel coronavirus disease (COVID-19)1, especially the significance of pulmonary CT scan plus blood routine examination for screening COVID-19. Due to the worldwide outbreak of infection in the past few months, there were quite a number of urgent hospital admissions for delivery, many effective measures have been taken to reduce the incidence of nosocomial infection and the expansion of the epidemic.
Source: Journal of Infection - Category: Infectious Diseases Authors: Source Type: research
AbstractObjectivesPrimary objective: to evaluate the efficacy of melatonin as a prophylactic treatment on prevention of symptomatic SARS-CoV-2 infection among healthcare workers at high risk of SARS-CoV-2 exposure.Secondary objectives:To evaluate the efficacy of melatonin as a prophylactic treatment on prevention of asymptomatic SARS-CoV-2 infection.To evaluate the efficacy of melatonin to prevent the development of severe COVID-19 in the participants enrolled in this study who develop SARS-CoV-2 infection along the trial.To evaluate the duration of COVID-19 symptoms in participants receiving melatonin before the infection...
Source: Trials - Category: Research Source Type: clinical trials
This study will be undertaken at the Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences and Health Services.Intervention and comparatorCOVID-19 confirmed patients will be randomly assigned to one of three groups, with 20 patients in each. The first group (Arm 1) will receive Hydroxychloroquine + Lopinavir / Ritonavir (Kaletra) + Interferon- β 1a (Recigen), the second group (Arm 2) will be administered Hydroxychloroquine + Lopinavir / Ritonavir (Kaletra) + Interferon-β 1b (Ziferon), and the control group (Arm 3) will be treated by Hydroxychloroquine + Lopinavir / Ritonavir (Kaletra).Main outcom...
Source: Trials - Category: Research Source Type: clinical trials
DiscussionWhile awaiting a vaccine, hygiene measures, social distancing and personal protective equipment are the only primary prophylaxis measures against SARS-CoV-2, but they have not been sufficient to protect our healthcare professionals. Some evidence of thein vitro efficacy of hydroxychloroquine against this virus is known, along with some clinical data that would support the study of this drug in the chemoprophylaxis of infection. However, there are still no data from controlled clinical trials in this regard. If our hypothesis is confirmed, hydroxychloroquine can help professionals fight this infection with more gu...
Source: Trials - Category: Research Source Type: clinical trials
Los Angeles County officials reported Monday an additional 22 coronavirus-linked deaths, including a pregnant woman who had tested positive for the virus and had underlying health issues and a person who was incarcerated in a jail facility.
Source: L.A. Times - Health - Category: Consumer Health News Authors: Source Type: news
The new study included 770 hospital patients who hadn't previously been diagnosed with coronavirus infection. Of those, 30 tested positive for COVID-19. Of those who tested positive, 22 had no symptoms -- meaning the rate of positive tests among asymptomatic women was 2.9%.
Source: WebMD Health - Category: Consumer Health News Source Type: news
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