Genome-Wide Association Study Identifies Genetic Associations with Perceived Age

Failure of dermal protection or repair mechanisms might lead to visibly aged skin. The study aimed to identify genetic associations with perceived age. A genome-wide association study was undertaken in 423,992 adult participants of UK Biobank, using questionnaire data on perceived age and genetic data imputed to the Haplotype Reference Consortium imputation panel. The study identified 74 independently associated genetic loci, to our knowledge previously unreported (P
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Original Article Source Type: research