Dual Therapy With Anti-CGRP Monoclonal Antibodies and Botulinum Toxin for Migraine Prevention: Is There a Rationale?
CONCLUSION: There is currently only indirect preclinical evidence to support a rationale for dual therapy with anti-calcitonin gene-related peptide monoclonal antibodies and botulinum toxin type A for chronic migraine prevention. Rigorous studies evaluating clinical efficacy, safety, and cost-effectiveness are needed.
PMID: 32437038 [PubMed - as supplied by publisher]
Source: Headache - Category: Neurology Authors: Pellesi L, Do TP, Ashina H, Ashina M, Burstein R Tags: Headache Source Type: research