The protective effects of adalimumab on intestinal injury induced with infrarenal aortic occlusion.

CONCLUSION: We found that ADA treatment reduced MDA levels and decreased the numerical density of caspase-3 and TNF-α positive enterocytes compared to the IR group (p=0.00; p=0.011; p=0.00, respectively). We conclude that ADA can be beneficial in preventing intestinal injury that arises from IR.
PMID: 32436975 [PubMed - in process]

Source: Turkish Journal of Trauma and Emergency Surgery : TJTES - April 30, 2020 Category: Emergency Medicine Authors: Pergel A, Tümkaya L, Demiral G, Çolakoğlu MK, Kalcan S, Özdemir A, Mercantepe T, Erdivanlı B, Yılmaz A Tags: Ulus Travma Acil Cerrahi Derg Source Type: research