Facile synthesis of kwakhurin, a marker compound of Pueraria mirifica and its quantitative NMR analysis for standardization as a reagent.

In this study, we described the facile synthesis of KWA, a marker compound of P. mirifica. Our revised synthetic method produced KWA with shorter steps and higher yield than the reported method. Furthermore, the absolute purity of KWA was determined by quantitative NMR analysis for standardization as a reagent, and its purity was 92.62 ± 0.12%. PMID: 32434998 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32434998?dopt=Abstract

Source: Chemical and Pharmaceutical Bulletin - May 20, 2020 Category: Drugs & Pharmacology Authors: Tsuji G, Yusa M, Masada S, Yokoo H, Hosoe J, Hakamatsuka T, Demizu Y, Uchiyama N Tags: Chem Pharm Bull (Tokyo) Source Type: research