Clinical and genetic analysis of lipoprotein glomerulopathy patients caused by APOE mutations
ConclusionHere, we report for the first timeAPOE‐Osaka/Kurashiki andAPOE‐Chicago mutations in the Chinese population. LPG was associated with higher blood pressure and serum apoE levels were higher in patients with mutations in LDL receptor binding region. In addition, the findings further indicated that treatment of proteinuria might slow down renal function progress ion in these patients.
Source: Molecular Genetics & Genomic Medicine - Category: Genetics & Stem Cells Authors: Mingxin Yang,
Qinjie Weng,
Xiaoxia Pan,
Hafiz Muhammad Jafar Hussain,
Shuwen Yu,
Jing Xu,
Xialian Yu,
Yunzi Liu,
Yuanmeng Jin,
Chunli Zhang,
Xiao Li,
Hong Ren,
Nan Chen,
Jingyuan Xie Tags: ORIGINAL ARTICLE Source Type: research