Clinical and genetic analysis of lipoprotein glomerulopathy patients caused by APOE mutations

ConclusionHere, we report for the first timeAPOE‐Osaka/Kurashiki andAPOE‐Chicago mutations in the Chinese population. LPG was associated with higher blood pressure and serum apoE levels were higher in patients with mutations in LDL receptor binding region. In addition, the findings further indicated that treatment of proteinuria might slow down renal function progress ion in these patients.
Source: Molecular Genetics & Genomic Medicine - Category: Genetics & Stem Cells Authors: Tags: ORIGINAL ARTICLE Source Type: research