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Dr. Jorge Rodriguez and CNN's medical correspondent Elizabeth Cohen discuss a new study that shows seriously ill Covid-19 patients treated with hydroxychloroquine, a drug touted by President Donald Trump to treat the virus, were more likely to die or develop dangerous heart arrhythmias.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news

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Hydroxychloroquine has been touted as a potential treatment for COVID-19, but new observational data show it is not only without benefit but it increases death and arrhythmias.Medscape Medical News
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Cardiology News Source Type: news
Seriously ill Covid-19 patients who were treated with hydroxychloroquine or chloroquine were more likely to die or develop dangerous irregular heart rhythms, according to a large observational study published Friday in the medical journal The Lancet.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news
Condition:   COVID-19 Intervention:   Device: C3+ Holter Monitor Sponsor:   Herlev and Gentofte Hospital Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
AbstractSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects host cells following binding with the cell surface ACE2 receptors, thereby leading to coronavirus disease 2019 (COVID-19). SARS-CoV-2 causes viral pneumonia with additional extrapulmonary manifestations and major complications, including acute myocardial injury, arrhythmia, and shock mainly in elderly patients. Furthermore, patients with existing cardiovascular comorbidities, such as hypertension and coronary heart disease, have a worse clinical outcome following contraction of the viral illness. A striking feature of COVID-19 pandemics is the hig...
Source: AGE - Category: Geriatrics Source Type: research
Hydroxychloroquine can cause arrhythmia, but the White House physician says the “potential benefit from treatment outweighed the relative risks.” Stocks rose after the release of encouraging data on a potential vaccine.
Source: NYT Health - Category: Consumer Health News Tags: Coronavirus (2019-nCoV) Source Type: news
AbstractCOVID-19 infection has shown rapid growth worldwide, and different therapies have been proposed for treatment, in particular, the combination of immune response modulating drugs such as chloroquine and hydroxychloroquine (antimalarials) alone or in combination with azithromycin. Although the clinical evidence supporting their use is scarce, the off label use of these drugs has spread very quickly in face of the progression of the epidemic and the high mortality rate in susceptible populations. However, these medications can pathologically prolong the QT interval and lead to malignant ventricular arrhythmias such th...
Source: Journal of Interventional Cardiac Electrophysiology - Category: Cardiology Source Type: research
Source: U.S. Food and Drug Administration (FDA). Published: 5/14/2020. This three-page fact sheet informs healthcare providers of the significant known and potential risks and benefits of the emergency use of the G Medical VSMS ECG Patch. The VSMS Patch is authorized for emergency use in the hospital setting for remote monitoring of the QT interval of an electrocardiogram (ECG) in general care (i.e., not in the intensive care unit) patients who are 18 years of age or older and are undergoing treatment for COVID-19 using drugs that can prolong the QT intervals and may cause life-threatening arrhythmias ( e.g., hydroxychlor...
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - Category: International Medicine & Public Health Source Type: news
Many COVID-19 trials have not looked at ECGs, either to exclude people at highest risk for a life-threatening cardiac arrhythmia or to flag people who achieve a dangerous QTc interval on treatment.Medscape Medical News
Source: Medscape Cardiology Headlines - Category: Cardiology Tags: Cardiology News Source Type: news
AbstractCOVID 19 is much more than an infectious disease by SARS-CoV-2 followed by a disproportionate immune response. An older age, diabetes and history of cardiovascular disease, especially hypertension, but also chronic heart failure and coronary artery disease among others, are between the most important risk factors. In addition, during the hospitalization both hyperglycaemia and heart failure are frequent. Less frequent are acute coronary syndrome, arrhythmias and stroke. Accordingly, not all prolonged stays or even deaths are due directly to SARS-CoV-2. To our knowledge, this is the first review, focusing both on ca...
Source: The Journal of Nutrition, Health and Aging - Category: Nutrition Source Type: research
The COVID-19 pandemic poses a significant stress on health resources in Australia. The Heart Rhythm Council of the Cardiac Society of Australia and New Zealand aims to provide a framework for efficient resource utilisation balanced with competing risks when appropriately treating patients with cardiac arrhythmias. This document provides practical recommendations for the electrophysiology (EP) and cardiac implantable electronic devices (CIED) services in Australia. The document will be updated regularly as new evidence and knowledge is gained with time.
Source: Heart, Lung and Circulation - Category: Cardiology Authors: Tags: Position Statement Source Type: research
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