Nanomaterials-based Cell Osteogenic Differentiation and Bone Regeneration.

Nanomaterials-based Cell Osteogenic Differentiation and Bone Regeneration. Curr Stem Cell Res Ther. 2020 May 20;: Authors: Zhang T, Gao Y, Cui W, Li Y, Xiao D, Zhou R Abstract With the rapid development of nanotechnology, various nanomaterials have been applied to bone repair and regeneration. Due to the unique chemical, physical and mechanical properties, nanomaterials could promote stem cells osteogenic differentiation, which has great potentials in bone tissue engineering and exploiting nanomaterials-based bone regeneration strategies. In this review, we summary current nanomaterials with osteo-induction ability, which could be potentially applied to bone tissue engineering. Meanwhile, the unique properties of these nanomaterials and their effects on stem cell osteogenic differentiation are also discussed. Furthermore, possible signaling pathways involved in the nanomaterialsinduced cell osteogenic differentiation are also highlighted in this review. PMID: 32436831 [PubMed - as supplied by publisher]
Source: Current Stem Cell Research and Therapy - Category: Stem Cells Authors: Tags: Curr Stem Cell Res Ther Source Type: research