Lower Grade Gliomas

This article reviews recent research on the clinical and molecular aspects of the disease and innovative therapeutic modalities in the process.Recent FindingsNewly identified clinical and molecular features are currently used in the classification of LGG and applied in treatment-planning decisions. Advanced studies on the cellular level have an advanced understanding of the metabolic effects induced by IDH mutations, offering opportunities for specific targeted therapies that may improve patient outcomes. Such findings may lead to a paradigm shift in the treatment of these tumors.SummaryAlthough LGG are sensitive to radiation and chemotherapy, these therapies are not curative, and patient survival remains limited, raising the need for more creative and effective interventions.
Source: Current Neurology and Neuroscience Reports - Category: Neuroscience Source Type: research