Females with cystic fibrosis have a larger decrease in sweat chloride in response to lumacaftor/ivacaftor compared to males

As it has been long known that the sweat gland is affected in Cystic Fibrosis (CF), the chloride concentration in induced sweat has been the gold standard in CF diagnostics for decades [1].

Source: Journal of Cystic Fibrosis - May 20, 2020 Category: Respiratory Medicine Authors: B.L. Aalbers, R.W. Hofland, I. Bronsveld, K.M. de Winter-de Groot, H.G.M. Arets, A.C. de Kiviet, M.M.M. van Oirschot-van de Ven, M.A. Kruijswijk, S. Schotman, S. Michel, C.K. van der Ent, H.G.M. Heijerman Source Type: research