Urinary HPV DNA testing as a tool for cervical cancer screening in women who are reluctant to have a Pap smear in France

In 2018, cervical cancer was the 4th most common cancer in women for incidence and mortality after breast, colorectal, and lung cancer.1 In France, in 2017, it was the 12th most common cancer with 2,800 new cases each year. Regarding mortality rate, it is 4th in the world (about 270,000 deaths per year), 1st in low-income countries, and 12th in France (about 1,100 deaths per year).2,3
Source: Journal of Infection - Category: Infectious Diseases Authors: Source Type: research

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Patients with pleural mesothelioma cancer may have another treatment option after the U.S. Food and Drug Administration approved the use of pembrolizumab for certain metastatic tumors this week. Pembrolizumab, often known by the brand name Keytruda, is a well-known immunotherapy drug already being used with mixed success for several cancers. This latest FDA approval is for the treatment of adult and pediatric cancers with unresectable disease and high mutational burden that have progressed following prior treatment and have no alternative treatment options. A number of mesothelioma patients already are being treated with p...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Source Type: news
ConclusionsExposure to PM2.5 air pollution contributes to lung cancer mortality and may be a risk factor for other cancer types. Cigarette smoking has a larger impact on cancer mortality than PM2.5 , but is associated with similar cancer types.
Source: Cancer Causes and Control - Category: Cancer & Oncology Source Type: research
Abstract Cervical cancer is the fourth most common gynecological malignancy affecting the health of women worldwide and the second most common cause of cancer‑related mortality among women in developing regions. Thus, the development of effective chemotherapeutic drugs for the treatment of cervical cancer has become an important issue in the medical field. The application of natural products for the prevention and treatment of various diseases, particularly cancer, has always attracted widespread attention. In the present study, a library of natural products composed of 78 single compounds was screened and ...
Source: International Journal of Oncology - Category: Cancer & Oncology Authors: Tags: Int J Oncol Source Type: research
Conclusions: Based on the findings in this study, we suggest that FDG PET/MRI might be an effective cancer screening modality, especially in combination with lung CT. Table 1.The cancer type distribution of the subjectsNumber of casesorganShanghaiHangzhouTotalLung461561Thyroid527Breast415Digestive system (Stomach, Colon)4(1,3)1(1,0)5Urogenital system (Kidney, Prostate, Cervical)7(2,4,1)1(0,1,0)8Nasopharynx213Tonsil101Total692190Table 2. False positive cases detected by PET/MROrganShanghaiHangzhouTotalThyroid10616Colon112Stomach101Breast202Total14721Table 3.False negative cases missed by PET/MRNO.CenterAgeSexOrganHistologic...
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Miscellaneous Source Type: research
umar B Kunnumakkara According to the World Health Organization (WHO), cancer is the second-highest cause of mortality in the world, and it kills nearly 9.6 million people annually. Besides the fatality of the disease, poor prognosis, cost of conventional therapies, and associated side-effects add more burden to patients, post-diagnosis. Therefore, the search for alternatives for the treatment of cancer that are safe, multi-targeted, effective, and cost-effective has compelled us to go back to ancient systems of medicine. Natural herbs and plant formulations are laden with a variety of phytochemicals. One such compound ...
Source: Molecules - Category: Chemistry Authors: Tags: Review Source Type: research
Screening and monitoring tests for breast, prostate, colorectal, cervical, and lung cancer have substantially decreased because of the pandemic.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news
CONCLUSION: Long non-coding RNA DLEU1 is likely to represent an available biomarker or a potential therapeutic target in multiple tumors. PMID: 31969095 [PubMed - as supplied by publisher]
Source: Current Pharmaceutical Design - Category: Drugs & Pharmacology Authors: Tags: Curr Pharm Des Source Type: research
Synlett DOI: 10.1055/s-0039-1690781 In this work, 21 novel (1,4-disubstituted 1,2,3-triazole)-dihydropyrimidinone (1,2,3-trzl-DHPM) type hybrids were synthesized and characterized. These were divided into two types: hybrids A (5 in total) containing the dihydropyrimidinone heterocyclic ring decorated with a 1,4-disubstituted 1,2,3-triazole in the C-5 position [these compounds were accessed by a multicomponent copper(I)-catalyzed azide alkyne cycloaddition (CuAAC) (or click)–Biginelli reactions with satisfactory yields (39–57%)] and hybrids B (16 in total) containing two 1,2,3-triazole units in the C-5 and C-6 m...
Source: Synlett - Category: Chemistry Authors: Tags: letter Source Type: research
Breakthrough treatments for lung cancer and melanoma have driven down cancer mortality overall — and from 2016 to 2017 spurred the largest-ever decline.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Cancer Smoking and Tobacco Lung Cancer Colon and Colorectal Cancer Breast Cancer Cervical Cancer Prostate Cancer Obesity American Cancer Society your-feed-healthcare Source Type: news
ConclusionsSubstantial differences in cancer incidences were founded depending on occupation reflecting socioeconomic position, in the Korean working population. Cancer prevention policy should focus on addressing these socioeconomic inequalities.
Source: Safety and Health at Work - Category: Occupational Health Source Type: research
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