Type 1 and Type 2 diabetes and COVID-19 related mortality in England, NHS England

Population cohort study (263,830&2,864,670 people with type 1&2 diabetes respectively) found crude mortality rates for COVID-19 in people with diabetes of 138.3 and 260.6 per 100,000 persons for type 1&2 respectively, with general population rate being 38.8/100,000.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news

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This study revealed the association between PAH exposure and markers of inflammation and oxidative stress, and the enhanced responses of pre-T2D patients suggested that individuals with metabolic disorders were more susceptible to the adverse health effects of PAH exposure. PMID: 32464779 [PubMed - in process]
Source: Chemosphere - Category: Chemistry Authors: Tags: Chemosphere Source Type: research
In this study, five machine learning algorithms and twelve types of molecular fingerprints were employed to generate QSAR discriminant models for mitochondrial toxicity. A threshold moving method was adopted to resolve the imbalance issue in the training data. Consensus of the models by an averaging probability strategy improved prediction performance. The best model has correct classification rates of 81.8% and 88.3% in ten-fold cross validation and external validation, respectively. Substructures such as phenol, carboxylic acid, nitro and arylchloride were found informative through analysis of information gain and freque...
Source: Chemosphere - Category: Chemistry Authors: Tags: Chemosphere Source Type: research
I have results from my clinic… Three of my diabetic patients went into remission after using hyperbaric oxygen therapy (HBOT). Two patients had type 1 diabetes… and another had type 2 diabetes. All three recovered with oxygen therapy. Most mainstream doctors would scoff at the idea… they “know” there’s no cure for diabetes. And to be treated for it with oxygen seems laughable. If you’re a regular reader, you know more about oxygen therapy than 99% of the general public, including most doctors. But the reason diabetes responds so well to oxygen may surprise you… It al...
Source: Al Sears, MD Natural Remedies - Category: Complementary Medicine Authors: Tags: Health Source Type: news
The risk of death from COVID-19 is three and a half times higher for patients with type 1 diabetes and two times higher for those with type 2 diabetes, compared with people without the condition, new NHS research shows.
Source: GP Online News - Category: Primary Care Tags: Coronavirus Source Type: news
NHS ’s first breakdown of underlying health conditions also finds 18% had dementiaCoronavirus – latest updatesSee all our coronavirus coverageOne in four people who havedied in hospital with Covid-19 also had diabetes, the NHS ’s first breakdown of underlying health conditions among the fatalities shows.Of the 22,332 people who died in hospital in England between 31 March and 12 May, 5,873 (26%) suffered from either type 1 or type 2 diabetes, NHS England figures reveal.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Coronavirus outbreak UK news Diabetes Heart disease Dementia NHS Hospitals Health Infectious diseases Medical research Mental health Microbiology Science Society Source Type: news
Diabetes Core Update: Covid-19 and Diabetes – Considerations for Health Care Professionals - April 2019 This special issue is an audio version of the American Diabetes Associations Covid-19 leadership team discussing a range of issues on Covid-19 and Diabetes. Recorded March 31, 2020. Topics include: Access to medications Effect on Diabetes Self-management Can Patients take their own Supplies if they are an inpatient in the hospital – particularly insulin pumps and CGM Considerations for Specific Hypoglycemic Medications during Inpatient Hospitalization Differences in Management for Persons with Type 1 and Type...
Source: Diabetes Core Update - Category: Endocrinology Authors: Source Type: podcasts
Preliminary data from China suggest that people with diabetes and other preexisting conditions are more likely to experience serious complications and death from COVID-19 than people without diabetes and other conditions. But COVID-19 and the coronavirus that causes it are new, and researchers are still investigating how they impact immunity. We also know that if a person has diabetes and gets influenza or another infection, they can experience worse health outcomes. The question is why. High blood sugars can interfere with white blood cells’ ability to fight infection. So there’s a possibility that people with...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Diabetes Health Source Type: blogs
This study is par for the course, looking at Japanese Olympic participants. Interestingly, it hints at the upper end of the dose-response curve for physical activity, in that a longer career as a professional athlete may be detrimental in comparison to lesser degrees of exercise and training. From this large, retrospective cohort study targeting 3546 Japanese Olympic athletes, we observed significant lower mortality among Olympians compared with the Japanese general population. The overall standardised mortality ratio (SMR) was 0.29. The results were consistent with previous studies conducted in other non-Asian co...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
How might COVID-19 affect patients with well-controlled type 1 or type 2 diabetes? Dr Anne Peters comments on three patient cases.Medscape Diabetes &Endocrinology
Source: Medscape Diabetes Headlines - Category: Endocrinology Tags: Diabetes & Endocrinology Commentary Source Type: news
  If any reminder were needed of the power of collaboration in healthcare, it is the global efforts underway to stem the current coronavirus outbreak and to develop treatments for it.  Chris Round, Merck ’s Head of International Operations&Global Core Franchises, speaking to eyeforpharma ahead of his eyeforpharma Barcelona Conference 2020 keynote, mentions that Merck is lending its heft to industry efforts to help tackle the emergency. “The industry has shown what it is capable of with HIV and Ebola in the past, so I am hopeful that the industry can pull together very fast.”  Partner...
Source: EyeForPharma - Category: Pharmaceuticals Authors: Source Type: news
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