Sodium Tanshinone IIA Sulfonate Attenuates Tumor Oxidative Stress and Promotes Apoptosis in an Intermittent Hypoxia Mouse Model.

CONCLUSION: Intermittent hypoxia treatment resulted in high oxidative stress and low apoptosis in Lewis lung carcinoma-implanted mice, which could be attenuated by sodium tanshinone IIA sulfonate administration possibly through a mechanism mediated by the nuclear factor erythroid 2-related factor 2/nuclear factor kappa B signaling pathway. PMID: 32431212 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/32431212?dopt=Abstract

Source: Technology in Cancer Research and Treatment - December 31, 2019 Category: Cancer & Oncology Authors: Zhang XB, Chen XY, Sun P, Su XM, Zeng HQ, Zeng YM, Wang M, Luo X Tags: Technol Cancer Res Treat Source Type: research