Detection of promoter DNA methylation in urine and plasma aids the detection of non-small cell lung cancer.

CONCLUSION: DNA methylation-based biomarkers in plasma and urine could be useful as an adjunct to CT screening to guide decision-making regarding further invasive procedures in patients with pulmonary nodules.
PMID: 32430478 [PubMed - as supplied by publisher]

Source: Clinical Cancer Research - May 18, 2020 Category: Cancer & Oncology Authors: Liu B, Ricarte-Filho J, Mallisetty A, Villani C, Kottorou AE, Rodgers KP, Chen C, Ito T, Holmes K, Gastala N, Valyi-Nagy K, David O, Gaba RC, Ascoli C, Pasquinelli M, Feldman LE, Massad MG, Wang TH, Jusue-Torres I, Benedetti E, Winn RA, Brock MV, Herman J Tags: Clin Cancer Res Source Type: research