Prognostic significance of right ventricular hypertrophy and systolic function in Anderson –Fabry disease
AbstractAimsRight ventricular hypertrophy (RVH) is a common finding in Anderson –Fabry disease (AFD), but the prognostic role of right ventricular (RV) involvement has never been assessed. The aim of our study was to evaluate the prognostic significance of RVH and RV systolic function in AFD.Methods and resultsForty ‐five AFD patients (56% male patients) with extensive baseline evaluation, including assessment of RVH and RV systolic function, were followed‐up for an average of 51.2 ± 11.4 months. RV systolic function was assessed by standard and tissue Doppler echocardiography. Cardiovascular events wer e defined as new‐onset atrial fibrillation (AF), sustained ventricular arrhythmias, heart failure, or pacemaker/implantable cardioverter defibrillator implantation; renal events were defined as progression to dialysis and/or renal transplantation or significant worsening of glomerular filtration r ate; and cerebrovascular events were defined as transient ischaemic attack or stroke.Fourteen patients (31.1%) presented RVH, while RV systolic function was normal in all cases. During the follow ‐up period, 13 patients (28.8%, 11 male) experienced 18 major events, including two deaths. Cardiovascular events occurred in eight patients (17.7%). The most common event was pacemaker/implantable cardioverter defibrillator implantation (six patients, 13.3%), followed by AF (three cases, 6.6%). O nly one case of worsening New York Heart Association class ...
Publication date: Available online 3 July 2020Source: The Annals of Thoracic SurgeryAuthor(s): Laura Seese, Sameer Hirji, Ibrahim Sultan, Thomas Gleason, Arman Kilic
Conclusion: Our work represents the initial experience in the liver transplantation technique for thrombectomy in distinct and well-selected patients with atrial tumor thrombi. The effectiveness of this approach needs further study. The video presentation of our research took place in March 2019 at the 34th Annual EAU Congress in Barcelona. PMID: 32612649 [PubMed]
CONCLUSION: Saphenous vein dilation throughout the below-knee promotes fistula patency, but the posterior tibial artery shows inadequate response as an inflow supplier at the ankle level. More proximal connection of saphenous vein after balloon dilation may be used in the future to achieve adequate flow from leg arteries. PMID: 32611233 [PubMed - as supplied by publisher]
Publication date: Available online 24 June 2020Source: Saudi Journal of Biological SciencesAuthor(s): Neda M. Bogari, Ashwag Aljohani, Anas Dannoun, Osama Elkhateeb, Masimo Porqueddu, Amr A. Amin, Dema N. Bogari, Mohiuddin M. Taher, Faruk Buba, Reem M. Allam, Mustafa N. Bogari, Francesco Alamanni
CONCLUSION: discharge planning based on the NIC improves the NOC score and may interfere in the health outcomes. PMID: 32609201 [PubMed - in process]
CONCLUSIONS: it highlights the importance of directing health promotion for caregivers, inserting them in the care process, recognizing their needs and intensifying practices that promote empowerment for care, bypassing curative actions. PMID: 32609175 [PubMed - in process]
Abstract In recent years, home medical care has been strongly promoted. As a consequence, the conditions managed in home medical care have become increasingly diverse. Heart failure is one of the most common disorders after malignant diseases. Patients with chronic heart failure (CHF) are often forced into hospitalization because of the inability to control symptoms with oral medications, even though they hope to stay at home. Recently, we have experienced a case where the patient required continuous administration of dobutamine at home. In order to carry out CHF care at home successfully, it is necessary to adjus...
Abstract Because the brain is the most important human organ, many brain disorders can cause severe symptoms. For example, glioma, one type of brain tumor, is progressive and lethal, while neurodegenerative diseases cause severe disability. Nevertheless, medical treatment for brain diseases remains unsatisfactory, and therefore innovative therapies are desired. However, the development of therapies to treat some cerebral diseases is difficult because the blood-brain barrier (BBB) or blood-brain tumor barrier prevents drugs from entering the brain. Hence, drug delivery system (DDS) strategies are required to delive...
Authors: Valle FH, Matte BS, Brum J, Clausell N, Goldraich LA Abstract Coronary-to-cardiac chamber fistulae and coronary aneurysms are potential complications after heart transplantation. In the setting of exercise intolerance and large fistulae at major coronary vessels, covered stents may provide an effective interventional strategy. PMID: 32610274 [PubMed - in process]
Authors: Basu S, Kumar NS, Sekhar U PMID: 32610884 [PubMed - in process]