Polycomb-like 2 regulates PRC2 components to affect proliferation in glioma cells

ConclusionsAs an important accessory protein of PRC2, PCL2 can not only change the expression of PRC2 components, but also affect the expression level of Histone methylation. Therefore, PCL2 may be an important hub for regulating the synergy among PRC2 members. This study revealed PCL2 as a new target for tumor research and open up a new avenue for future research in glioma.
Source: Journal of Neuro-Oncology - Category: Cancer & Oncology Source Type: research