[Research Articles] An open-label phase 1/2a trial of a genetically modified rodent malaria parasite for immunization against Plasmodium falciparum malaria

This study demonstrates that PbVac immunization elicits a marked biological effect, inhibiting a subsequent infection by the human Pf parasite, and establishes the clinical validation of a new paradigm in malaria vaccination.

Source: Science Translational Medicine - May 19, 2020 Category: Biomedical Science Authors: Reuling, I. J., Mendes, A. M., de Jong, G. M., Fabra-Garcia, A., Nunes-Cabaco, H., van Gemert, G.-J., Graumans, W., Coffeng, L. E., de Vlas, S. J., Yang, A. S. P., Lee, C., Wu, Y., Birkett, A. J., Ockenhouse, C. F., Koelewijn, R., van Hellemond, J. J., va Tags: Research Articles Source Type: research