Dementia care: Easy-to-do activities to reduce risk of dementia, according to study

DEMENTIA is a condition which entails the degeneration of the brain. A latest study sheds light on how this condition could be reduced.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news

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CONCLUSION: Neurocognitive progression in MD1 seems to respond to a progressive pattern of degeneration, linked to the functions that are most affected from the beginning of the sequelae phase and which usually correspond to the domains of working memory, alternating attention, and visuospatial and visuoconstructive abilities. PMID: 32436207 [PubMed - in process]
Source: Revista de Neurologia - Category: Neurology Authors: Tags: Rev Neurol Source Type: research
CONCLUSIONS: There seems to be a weak association between benzodiazepine use and the development of dementia, the risk increases with greater exposure. PMID: 32434656 [PubMed - as supplied by publisher]
Source: Medicina Clinica - Category: General Medicine Tags: Med Clin (Barc) Source Type: research
Publication date: June 2020Source: Healthcare, Volume 8, Issue 2Author(s): Barbara N. Harding, James S. Floyd, Jeffrey F. Scherrer, Joanne Salas, John E. Morley, Susan A. Farr, Sascha Dublin
Source: Healthcare - Category: Middle East Health Source Type: research
AbstractBecause of the importance of cholesterol metabolism in the physiopathogenesis of dementia, and knowing the function of ATP-binding cassette A1 transporter (ABCA1) as a cholesterol flow pump at the cellular and cerebral level, it has been noted that the ABCA1 gene may be a good candidate for disease study. In order to evaluate the relationship between ABCA1 genetic variants and the risk of Alzheimer ’s disease and other dementia in Mexican individuals, we examined three ABCA1 polymorphisms located in the exonic region (rs2230808, rs2066718, rs2230806) and two in the promoter region (rs1800977, rs2422493) in a ...
Source: Metabolic Brain Disease - Category: Neurology Source Type: research
AbstractAmyotrophic lateral sclerosis (ALS) and hereditary spastic paraplegia (HSP) are motor neuron diseases sharing clinical, pathological, and genetic similarities. While biallelicSPG7 mutations are known to cause recessively inherited HSP, heterozygousSPG7 mutations have repeatedly been identified in HSP and recently also in ALS cases. However, the frequency and clinical impact of rareSPG7 variants have not been studied in a larger ALS cohort. Here, whole-exome (WES) or targetedSPG7 sequencing was done in a cohort of 214 European ALS patients. The consequences of a splice site variant were analyzed on the mRNA level. T...
Source: Journal of Neurology - Category: Neurology Source Type: research
Alzheimer's disease (AD) is the most common form of dementia, accounting for 50-75% of all cases, with a greater proportion of individuals affected at older age range. A single moderate or severe traumatic brain injury (TBI) is associated with accelerated ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
CONCLUSION: All data indicated that the expression of miR-129-5p in AD mice and patients is significantly upregulated by physical exercise. The knockdown of miR-129-5p can abrogate the neuroprotective effect of exercise on cognition and neuroinflammation in AD mice. This study provides a novel insight into the molecular mechanisms underlying the neuroprotective effect of physical exercise in AD, and miR-129-5p may provide a novel therapeutic target for AD treatment. PMID: 32434194 [PubMed - as supplied by publisher]
Source: Dementia and Geriatric Cognitive Disorders - Category: Psychiatry Tags: Dement Geriatr Cogn Disord Source Type: research
Cognition is an important function of the brain that enables us to acquire and process information, to enhance our understanding of thoughts, experiences, and our senses. Any condition that affects our ability to think, reason, memorize, or be attentive affects our cognitive ability. Some cognitive decline is a normal part of aging, but there are many things you can do to prevent or forestall cognitive changes as you age, including when planning for surgery. Older adults are having more surgical procedures As our population ages and medicine and healthcare advances, more older adults are likely to develop serious condition...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Healthy Aging Managing your health care Memory Neurological conditions Prevention Surgery Source Type: blogs
Authors: Marinescu RV, Lorenzi M, Blumberg SB, Young AL, Planell-Morell P, Oxtoby NP, Eshaghi A, Yong KX, Crutch SJ, Golland P, Alexander DC Abstract We introduce Disease Knowledge Transfer (DKT), a novel technique for transferring biomarker information between related neurodegenerative diseases. DKT infers robust multimodal biomarker trajectories in rare neurodegenerative diseases even when only limited, unimodal data is available, by transferring information from larger multimodal datasets from common neurodegenerative diseases. DKT is a joint-disease generative model of biomarker progressions, which exploits bio...
Source: MICCAI International Conference on Medical Image Computing and Computer-Assisted Intervention - Category: Radiology Tags: Med Image Comput Comput Assist Interv Source Type: research
Condition:   Dementia Interventions:   Drug: 11C-MC1;   Drug: 11C-PS13 Sponsor:   National Institute of Mental Health (NIMH) Recruiting
Source: - Category: Research Source Type: clinical trials
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