Max and Keira's Law: Mum 'blown away' by organ transplant legacy
Max and Keira's Law will make all adults in England potential organ donors unless they opt out.
CONCLUSIONS: The SMs in PWIBDs and a craniotomy performed immediately before starting the process of determining brain death seem to be related to lengthening the TT-BD. PMID: 33029974 [PubMed]
CONCLUSION: DAAs are effective and safe in the treatment of recurrent HCV infection in LT recipients with history of HCC. Relapse to pre- and post-LT DAA therapy is associated with post-transplantation HCC recurrence. PMID: 33033569 [PubMed]
Authors: Singh G, Yoshida EM, Rathi S, Marquez V, Kim P, Erb SR, Salh BS Abstract Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths worldwide. If diagnosed early, curative treatment options such as surgical resection, loco-regional therapies, and liver transplantation are available to patients, increasing their chances of survival and improving their quality of life. Unfortunately, most patients are diagnosed with late stage HCC where only palliative treatment is available. Therefore, biomarkers which could detect HCC early with a high degree of sensitivity and specificity, may play...
Authors: Arab JP, Dirchwolf M, Álvares-da-Silva MR, Barrera F, Benítez C, Castellanos-Fernandez M, Castro-Narro G, Chavez-Tapia N, Chiodi D, Cotrim H, Cusi K, de Oliveira CPMS, Díaz J, Fassio E, Gerona S, Girala M, Hernandez N, Marciano S, Masson W, Mendez-Sanchez N, Leite N, Lozano A, Padilla M, Panduro A, Paraná R, Parise E, Perez M, Poniachik J, Restrepo JC, Ruf A, Silva M, Tagle M, Tapias M, Torres K, Vilar-Gomez E, Costa Gil JE, Gadano A, Arrese M Abstract Non-alcoholic fatty liver disease (NAFLD) currently represents an epidemic worldwide. NAFLD is the most frequently diagnosed chr...
This article reviews CTE disease based on its clinical and histological presentation, etiology and pathogenesis, and management and outcome. PMID: 33029133 [PubMed]
ConclusionsThe non-cirrhotic livers from pediatric patients with metabolic liver disease can be used as domino donor grafts for selected pediatric patients with different metabolic liver disease. D-APOLT achieves ideal recipient outcomes and provides a strategy to expand donor source for children.
Publication date: Available online 9 October 2020Source: Hepatobiliary &Pancreatic Diseases InternationalAuthor(s): Heng-Kai Zhu, Li Zhuang, Cheng-Ze Chen, Zhao-Dan Ye, Zhuo-Yi Wang, Wu Zhang, Guo-Hong Cao, Shu-Sen Zheng
Publication date: Available online 8 October 2020Source: Journal of Clinical and Experimental HepatologyAuthor(s): Arvinder S. Soin, Narendra S. Choudhary, Sanjay K. Yadav, Sanjiv Saigal, Neeraj Saraf, Amit Rastogi, Prashant Bhangui, Thiagarajan Srinivasan, Neelam Mohan, Sujeet K. Saha, Ankur Gupta, Rohan J. Chaudhary, Kamal Yadav, Swapnil Dhampalwar, Deepak Govil, Nikunj Gupta, Vijay Vohra
Publication date: Available online 8 October 2020Source: Journal of Clinical and Experimental HepatologyAuthor(s): Ravi Mohanka, Prashantha Rao, Mitul Shah, Amit Gupte, Vinayak Nikam, Mihir Vohra, Ruhi Kohli, Anurag Shrimal, Ankush Golhar, Ameya Panchwagh, Saurabh Kamath, Akash Shukla, Priyesh Patel, Somnath Chattopadhyay, Gaurav Chaubal, Yasmin Shaikh, Vidhi Dedhia, Shivali S. Sarmalkar, Ravikiran Maghade, Kavita Shinde
We examined the clinical characteristics and post-LT outcomes of patients with sarcoidosis using the United Network for Organ Sharing database from 1985 to 2016 and compared them to patients (entire cohort as well as age, gender, and year of LT-matched counterparts) with primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC). For the matched design, a conditional logistic regression was used for categorical variables and marginal generalized estimating equation regression models for continuous variables. Survival functions were constructed using the Kaplan-Meier estimator. Results: A total of 206 pat...