Granulomatosis with Polyangiitis and Acute Tubulointerstitial Nephritis in the Absence of Glomerulonephritis

We report a 77-year-old woman with well-controlled hypertension who presented with lethargy. She had received antimicrobial treatment with ceftriaxone, levofloxacin, and clarithromycin for acute sinusitis and pneumonia 2 weeks prior to presentation. Serum creatinine was 51 µmol/L at that time. At presentation, she had acute kidney injury with peak serum creatinine of 482 µmol/L and required dialysis. Urine analysis noted few isomorphic red blood cells and white blood cells and proteinuria of 2.03 g/24 h.

Source: The American Journal of Medicine - April 19, 2020 Category: General Medicine Authors: Weiwen Guo, Keng Thye Woo, Jason CJ Choo, Puay Hoon Tan, Cynthia Ciwei Lim Tags: Clinical Communication to the Editor Source Type: research