Prevalence and characterization of plasmid mediated quinolone resistance determinants qnr and aac(6')-Ib-cr in ciprofloxacin resistant Escherichia coli isolates from commercial layer in Korea.

Prevalence and characterization of plasmid mediated quinolone resistance determinants qnr and aac(6')-Ib-cr in ciprofloxacin resistant Escherichia coli isolates from commercial layer in Korea. J Microbiol Biotechnol. 2020 May 15;: Authors: Seo K, Lee Y Abstract Prevalence and characterization of plasmid-mediated quinolone-resistance (PMQR) determinants genes of ciprofloxacin resistant Escherichia coli in Korea commercial layer farm was studied. Total of 45 ciprofloxacin-resistant E. coli isolates were recovered and all isolates were multidrug-resistance. Eight-isolates have the PMQR genes aac(6')-Ib-cr, qnrS1, and qnrB4 and seven-isolates exhibited double amino acid exchange at both gyrA and parC, and have high fluoroquinolone minimum inhibitory concentrations. Five transconjugants demonstrated transferability of PMQR and β-lactamase genes and similar antimicrobial resistance. Because PMQR genes in isolates from commercial layer chickens could enter the food supply and directly affect humans, control of ciprofloxacin resistance is needed. PMID: 32423191 [PubMed - as supplied by publisher]
Source: Journal of Microbiology and Biotechnology - Category: Biotechnology Authors: Tags: J Microbiol Biotechnol Source Type: research