Mass spectrometric analysis of 7-oxygenated androst-5-ene structures. Influence in trimethylsilyl derivatives formation.

CONCLUSIONS: The derivatization reagent, instrument conditions (inlet), as well as the chemical structures of the analytes present in the matrix can influence the results. So, before describing a new feature as a potential "new" metabolite, special caution must be taken since we could actually be dealing with an artifact.
PMID: 32424893 [PubMed - as supplied by publisher]

Source: Rapid Communications in Mass Spectrometry : RCM - May 17, 2020 Category: Chemistry Authors: Martinez-Brito D, de la Torre X, Parr MK, Botrè F Tags: Rapid Commun Mass Spectrom Source Type: research