A minor structure modification serendipitously leads to a highly carbapenemase-specific fluorogenic probe

Org. Biomol. Chem., 2020, Advance Article DOI: 10.1039/D0OB00114G, CommunicationJie Wang, Weipan Xu, Shuyuan Xue, Tao Yu, Hexin Xie A carbapenem-based fluorogenic reagent has been developed to detect the activity of carbapenemases, exhibiting high specificity to all carbapenemases, including both metallo carbapenemases and serine carbapenemases, over other β-lactamases. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research