Acute qt interval modifications during hydroxychloroquine-azithromycin treatment in the context of covid-19 infection.

Among candidate drugs to treat COVID-19, the combination of hydroxychloroquine (HCQ) and azithromycin (AZ) has received intense attention. Even if the efficacy of this combination is under evaluation, clinicians have begun to use it largely. As these medications are known to prolong QT interval, we analyzed serial electrocardiograms (ECG) performed in patients hospitalized for COVID-19 pneumonia and treated with HCQ + AZ.50 consecutive patients received the combination of HCQ (600mg/d for 10 days) and AZ (500mg Day 1 and 250mg daily days 2 to 5).
Source: Mayo Clinic Proceedings - Category: Internal Medicine Authors: Tags: Brief Report Source Type: research