Antibodies May Tame Inflammatory Condition in Kids

The inflammatory condition mimics some of the symptoms seen in toxic shock syndrome and a serious heart condition called Kawasaki disease.
Source: WebMD Health - Category: Consumer Health News Source Type: news

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Multisystem inflammatory syndrome in children (MIS-C) is a newly recognized condition affecting children with recent infection or exposure to coronavirus disease 2019 (COVID-19). MIS-C has symptoms that affect multiple organs systems, with some clinical features resembling Kawasaki disease (KD) and toxic shock syndrome (TSS).
Source: The Journal of Emergency Medicine - Category: Emergency Medicine Authors: Tags: Clinical Review Source Type: research
We report a 22-year-old Indian male, with five days of fever, headache, myalgia, skin rash and one day history of lower extremity and upper abdominal pain, and vomiting. COVID-19 Reverse transcriptase polymerase chain reaction (RT-PCR) at admission was negative.PMID:34115386 | DOI:10.1111/bjd.20574
Source: The British Journal of Dermatology - Category: Dermatology Authors: Source Type: research
AbstractWith growing number of pediatric cases of COVID-19, a unique hyper-inflammatory syndrome, linked to SARS-CoV-2 infection, has emerged in children referred to as multisystem inflammatory syndrome in children (MIS-C). This Kawasaki Disease (KD)-like illness has been described across the world. This syndrome shares features of KD, toxic shock syndrome, and macrophage activation syndrome and is associated with significantly elevated inflammatory markers. Everyday there are new data emerging improving the care of these patients. The Advanced Cardiac Therapies Improving Outcomes Network (ACTION) is a collaborative networ...
Source: Mammalian Genome - Category: Genetics & Stem Cells Source Type: research
Background: COronaVIrus Disease 2019 (COVID-19) affects children with less severe symptoms than adults. However, severe COVID-19 paediatric cases are increasingly reported, including patients with Kawasaki disease (KD) or a multisystem inflammatory syndrome (MIS-C) that can present with features resembling KD.Summary: MIS-C is an emerging severe paediatric syndrome associated with COVID-19 that can show overlapping features of KD, KD shock syndrome, and toxic shock syndrome. MIS-C might be an inflammatory disease distinct from KD resulting from an exaggerated immune response. A high prevalence of mucocutaneous manifestatio...
Source: Dermatology - Category: Dermatology Source Type: research
Orv Hetil. 2021 Apr 10;162(17):652-667. doi: 10.1556/650.2021.32231.ABSTRACTÖsszefoglaló. A SARS-CoV-2-fertőzés ritka gyermekkori szövődménye a sokszervi gyulladás, angol terminológiával paediatric inflammatory multisystem syndrome (PIMS). Két vagy több szerv érintettségével járó, súlyos tünetekkel induló betegségről van szó, amelynek tünetei átfedést mutatnak a Kawasaki-betegséggel, a toxikus sokk szindrómával és a makrofágaktivá...
Source: Orvosi Hetilap - Category: General Medicine Authors: Source Type: research
Orv Hetil. 2021 Apr 10;162(17):652-667. doi: 10.1556/650.2021.32231.ABSTRACTÖsszefoglaló. A SARS-CoV-2-fertőzés ritka gyermekkori szövődménye a sokszervi gyulladás, angol terminológiával paediatric inflammatory multisystem syndrome (PIMS). Két vagy több szerv érintettségével járó, súlyos tünetekkel induló betegségről van szó, amelynek tünetei átfedést mutatnak a Kawasaki-betegséggel, a toxikus sokk szindrómával és a makrofágaktivá...
Source: Orvosi Hetilap - Category: General Medicine Authors: Source Type: research
Orv Hetil. 2021 Apr 10;162(17):652-667. doi: 10.1556/650.2021.32231.ABSTRACTÖsszefoglaló. A SARS-CoV-2-fertőzés ritka gyermekkori szövődménye a sokszervi gyulladás, angol terminológiával paediatric inflammatory multisystem syndrome (PIMS). Két vagy több szerv érintettségével járó, súlyos tünetekkel induló betegségről van szó, amelynek tünetei átfedést mutatnak a Kawasaki-betegséggel, a toxikus sokk szindrómával és a makrofágaktivá...
Source: Orvosi Hetilap - Category: General Medicine Authors: Source Type: research
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