Fatal prostate cancer incidence trends in the United States and England by race, stage, and treatment
British Journal of Cancer, Published online: 20 May 2020; doi:10.1038/s41416-020-0859-xFatal prostate cancer incidence trends in the United States and England by race, stage, and treatment
AbstractTo evaluate the efficacy and safety of holmium laser enucleation of prostate (HoLEP) for treating urinary retention in patients with advanced prostate cancer. Thirty-eight cases of advanced prostate cancer with urinary retention were enrolled in this retrospective study. All the 38 patients were treated with CAB as a basis. Among them, 21 cases chose HoLEP additionally (HoLEP group). Seventeen cases stuck to CAB alone (CAB group). Serum PSA level, International Prostate Symptom Score (IPSS), quality of life score (QoLs), maximal flow rate (Qmax), and post-void residual volume (PVR) at 3, 6, 12, and 18 months after ...
Conditions: Prostate Cancer; Prostate Adenocarcinoma Interventions: Radiation: External Beam Radiation; Radiation: HDR Brachytherapy; Drug: Androgen Deprivation Therapy Sponsor: University of Virginia Not yet recruiting
Discussion: The goal of this trial is to determine the potential benefit of ALA-SFC in patients who undergo LDR-BT. To the best of our knowledge, this is the first study investigating the potential clinical benefit of oral ALA-SFC after radiotherapy. More evidence from a further randomized controlled trial is needed to change the standard of care and lead to better post-radiotherapy management. Trial registration: This clinical trial was prospectively registered with the Japan Registry of Clinical Trials on 5 December 2019. The reference number is jRCTs051190077, nara0013 (Certified Review Board of Nara Medical Univer...
PMID: 32637660 [PubMed]
Authors: Enikeev D, Taratkin M, Morozov A, Shpikina A, Singla N, Rivas JG, Barret E, Glybochko P PMID: 32638576 [PubMed - as supplied by publisher]
(University of California - San Francisco) Black men in the United States are known to suffer disproportionately from prostate cancer, but few studies have investigated whether genetic differences in prostate tumors could have anything to do with these health disparities. Now, in the largest study of its kind to date, researchers from Boston University School of Medicine (BUSM), UC San Francisco (UCSF), and Northwestern University have identified genes that are more frequently altered in prostate tumors from men of African ancestry compared to other racial groups.
Publication date: Available online 9 July 2020Source: European UrologyAuthor(s): Egesta Lopci, Massimo Lazzeri
Publication date: Available online 9 July 2020Source: European UrologyAuthor(s): Vasilis Stavrinides, Francesco Giganti, Mark Emberton, Caroline M. Moore
This study consisted of (N = 130) U.S. NIM, aged 40 years and older, who were recruited from local nonprofit associations in New Jersey. Pen-and-paper questionnaire data were gathered using the Behavioral Intention Scale and the modified version of the Champion’s Health Belief Model Scale for Prostate Cancer, along wi th demographic questions. Data were analyzed in SPSS 25.0. Multiple regression analysis was conducted to evaluate how well perceived susceptibility, benefits, and barriers predicted the intention to undergo screening for prostate cancer.ResultsThe model was significantly related to in...
Nature Reviews Urology, Published online: 10 July 2020; doi:10.1038/s41585-020-0358-0A new study describes the effects of androgen status on the different cell types in mouse and human prostates, illustrating the potential of single-cell RNA sequencing to study specific biological processes in unprecedented detail. Translating these new insights into clinical use will increase precision and personalization of prostate cancer treatment.