The dopamine receptor antagonist trifluoperazine prevents phenotype conversion and improves survival in mouse models of glioblastoma [Neuroscience]

We report that radiation induces a glioma-initiating cell phenotype, and we have identified trifluoperazine...

Source: Proceedings of the National Academy of Sciences - May 18, 2020 Category: Science Authors: Kruttika Bhat, Mohammad Saki, Erina Vlashi, Fei Cheng, Sara Duhachek-Muggy, Claudia Alli, Garrett Yu, Paul Medina, Ling He, Robert Damoiseaux, Matteo Pellegrini, Nathan R. Zemke, Phioanh Leia Nghiemphu, Timothy F. Cloughesy, Linda M. Liau, Harley I. Kornb Tags: Biological Sciences Source Type: research