Insights from experimental post-thrombotic syndrome and potential for novel therapies

Post thrombotic syndrome (PTS) is an end stage manifestation of deep vein thrombosis. This is an inherently inflammatory process, with consequent fibrosis. Multiple cellular types are involved, and are likely driven by leukocytes. Herein, we review the current gaps in therapy, and insights from rodent models of venous thrombosis that suggest possible targets to treat and prevent PTS.

Source: Translational Research - May 18, 2020 Category: Research Authors: Peter Henke, Sriganesh Sharma, Thomas Wakefield, Dan Myers, Andrea Obi Tags: Review Article Source Type: research