Molecular epidemiology and nitrofurantoin resistance determinants of nitrofurantoin-non-susceptible Escherichia coli isolated from urinary tract infections
Publication date: June 2020Source: Journal of Global Antimicrobial Resistance, Volume 21Author(s): Fatemeh Mottaghizadeh, Hanieh Mohajjel Shoja, Mehri Haeili, Davood Darban-Sarokhalil
Publication date: Available online 30 June 2020Source: Journal of Global Antimicrobial ResistanceAuthor(s): Juan Xu, Wenping Lin, Yanmin Chen, Fang He
Publication date: September 2020Source: Journal of Global Antimicrobial Resistance, Volume 22Author(s): Nahid Karami, Anna Lindblom, Shora Yazdanshenas, Viktoria Lindén, Christina Åhrén
Conclusions: Among the most common pathogens isolated from hospitalized patients with cUTI, the rates of single resistance to common treatments and of cross-resistance to these regimens are substantial. Knowing the patterns of cross-resistance may help clinicians tailor empiric therapy more precisely. PMID: 32423953 [PubMed - as supplied by publisher]
In conclusion, the most interesting finding is the association of iss with septic shock. Adhesins are important for UTI pathogenesis, while otherwise low-pathogenic isolates from the microbiota can cause post-prostate biopsy sepsis. PMID: 32423949 [PubMed - as supplied by publisher]
In this study, we aimed to investigate the burden of antimicrobial resistance and occurrence of ESBL genes among clinical isolates of uropathogenic Escherichia coli at a tertiary care teaching hospital of Nepal. During the study period, we processed a total of 1,626 urinary tract specimens, isolated significant bacterial pathogens, and investigated their antimicrobial susceptibilities. Escherichia coli (n = 154), the predominant pathogen associated with UTI, was further investigated for the existence of ESBL enzymes by using conventional phenotypic as well as molecular approaches. Among suspected cases of UTI...
ConclusionsIn ESBL-E. coli RUTI, most recurrences were caused by the initial infecting strain. The high frequency of the multidrug-resistant fimH30Rx subclone and its association with multiple recurrences warrants further attention and early detection of this subclone in patients at risk of developing RUTI with ESBL-producing E. coli.
ConclusionsOur study shows that fosfomycin-resistantE. coli strains are isolated in the majority of the cases in elderly people with complicated UTIs and belong the pandemic ST131 clone. To our knowledge, we describe, for the first time in Spain, the gene fosA3, which alerts for a future dissemination that should be monitored.
Antimicrobial resistance in N'Djamena (Chad): Four-year experience of the French Forward Medical and Surgical Team engaged in the "Barkhane Operation". Med Mal Infect. 2020 Feb 05;: Authors: Cardinale M, Bourbotte-Salmon F, Scheiwe C, Boulezaz S, Ridet M, Laitselart P Abstract OBJECTIVES: Knowledge of local antimicrobial resistance (AMR) patterns is required for effective empirical treatment of bacterial diseases. Very little is known about current resistance patterns of common pathogenic bacteria in the African region and particularly in the Sahel region. We aimed to describe the local bacte...
Conclusions:The results of this study showed that the most common resistance are antibiotics that are commonly used. The most effective antibiotics forE. coliwere imipenem, nitrofurantoin, amikacin, chloramphenicol, and ciprofloxacin. Considering this study, it had better, use less gentamicin, second ‑generation cephalosporins, and nalidixic acid in the initial treatment of infections caused byE. coli, and no use penicillins, tetracyclines, cotrimoxazole, and first-generation cephalosporins.Keywords:Antibiotics, antimicrobial resistance, Gram ‑negative bacteria, Gram‑positive bacteria, urinary tract infections
Abstract Diabetes mellitus is associated with various types of infections notably skin, mucous membrane, soft tissue, urinary tract, respiratory tract and surgical and/or hospital-associated infections. The reason behind this frequent association with infections is an immunocompromised state of diabetic patient because uncontrolled hyperglycemia impairs overall immunity of diabetic patient via involvement of various mechanistic pathways that lead to the diabetic patient as immunocompromised. There are specific microbes that are associated with each type of infection and their presence indicates specific type of in...