Cellular maps of gastrointestinal organs: getting the most from tissue clearing.

We present a brief overview of the chemical concepts that underpin tissue clearing, what sorts of questions whole-mount imaging can answer, how to choose a clearing agent, an example of how to clear and image alimentary tissue, and what to do after obtaining the image. This short review will encourage other gastrointestinal researchers to consider how utilizing tissue clearing and creating 3d "maps" of tissue might deepen the impact of their studies. PMID: 32421359 [PubMed - as supplied by publisher]
Source: American Journal of Physiology. Gastrointestinal and Liver Physiology - Category: Physiology Authors: Tags: Am J Physiol Gastrointest Liver Physiol Source Type: research