Risk factors for metachronous colorectal cancer in Lynch syndrome patients: a registry-based observational mono-institutional study cohort

ConclusionsAmong a high-risk population for CRC, in particular LS, an extended surgery may be considered in CRC patients with specific risk factors (MLH1 orMSH2 germline pathogenic variants, history of colorectal adenomas) to reduce the risk of mCRC development.

http://link.springer.com/10.1007/s10147-020-01700-2

Source: International Journal of Clinical Oncology - May 18, 2020 Category: Cancer & Oncology Source Type: research