Lp(a) concentration, genetic variants, apo(a) isoform size and cellular cholesterol efflux in subjects with elevated Lp(a) and coronary heart disease submitted or not to lipoprotein apheresis. The Italian case-control multicentre study on Lp(a)

Coronary artery disease(CAD) risk is greater with higher plasma lipoprotein(a)[Lp(a)] concentrations or smaller apoisoform size and putatively with increased cellular cholesterol loading capacity (CLC). The relationship between Lp(a) and CLC is not known. Information on Lp(a) polymorphisms in Italian patients is lacking.

Source: Journal of Clinical Lipidology - May 17, 2020 Category: Lipidology Authors: C. Stefanutti, L. Pisciotta, E. Favari, S. Di Giacomo, F. Vacondio, M.G. Zenti, C. Morozzi, D. Berretti, D. Mesce, M. Vitale, A. Pasta, A. Ronca, A. Garuti, M. Manfredini, E. Angl és-Cano, S.M. Marcovina, G.F. Watts, the Multidisciplinary International G Tags: Original Research Source Type: research