The prevalence and implications of single nucleotide polymorphisms in genes encoding the RNA polymerase of clinical isolates of Staphylococcus aureus

We present evidence for the existence of several, hitherto unreported, nonsynonymous SNPs in genes encoding the RNAP and associated factors of MRSA ST22 clinical isolates and propose that the acquisition of amino acid substitutions in the RNAP could represent an adaptive strategy that contributes to the pathogenic success of MRSA.

Source: MicrobiologyOpen - May 16, 2020 Category: Microbiology Authors: Aishwarya Krishna, Bing Liu, Sharon J. Peacock, Sivaramesh Wigneshweraraj Tags: COMMENTARIES Source Type: research