Intra ‐articular AAV‐PHP.S mediated chemogenetic targeting of knee‐innervating dorsal root ganglion neurons alleviates inflammatory pain in mice

ConclusionsWe describe an AAV ‐mediated chemogenetic approach to specifically control joint pain, which may be utilized in translational arthritic pain research.

Source: Arthritis and Rheumatology - May 16, 2020 Category: Rheumatology Authors: Sampurna Chakrabarti, Luke A. Pattison, Balint Doleschall, Rebecca H. Rickman, Helen Blake, Gerard Callejo, Paul A. Heppenstall, Ewan St. John Smith Tags: FULL LENGTH Source Type: research