MiR-200c-3p suppression is associated with development of acquired resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors in EGFR mutant non-small cell lung cancer via a mediating epithelial-to-mesenchymal transition (EMT) process.

CONCLUSION: MiR-200c-3p plays a role in sensitivity to EGFR TKIs via modulating EMT process.
PMID: 32417760 [PubMed - as supplied by publisher]

Source: Cancer Biomarkers : Section A of Disease Markers - May 8, 2020 Category: Cancer & Oncology Authors: Wang HY, Liu YN, Wu SG, Hsu CL, Chang TH, Tsai MF, Lin YT, Shih JY Tags: Cancer Biomark Source Type: research