Committee Opinion No. 399: Management of Tick Bites and Lyme Disease During Pregnancy: (En fran çais : Prise en charge des morsures de tiques et de la maladie de Lyme pendant la grossesse).
Committee Opinion No. 399: Management of Tick Bites and Lyme Disease During Pregnancy: (En français : Prise en charge des morsures de tiques et de la maladie de Lyme pendant la grossesse). J Obstet Gynaecol Can. 2020 May;42(5):644-653 Authors: Smith GN, Moore KM, Hatchette TF, Nicholson J, Bowie W, Langley JM Abstract OBJECTIVE: Lyme disease is an emerging infection in Canada caused by the bacterium belonging to the Borrelia burgdorferi sensu lato species complex, which is transmitted via the bite of an infected blacklegged tick. Populations of blacklegged ticks continue to expand and are now established in different regions in Canada. It usually takes more than 24 hours of tick attachment to transfer B. burgdorferi to a human. The diagnosis of early localized Lyme disease is made by clinical assessment, as laboratory tests are not reliable at this stage. Most patients with early localized Lyme disease will present with a skin lesion (i.e., erythema migrans) expanding from the tick bite site and/or non-specific "influenza-like" symptoms (e.g., arthralgia, myalgia, and fever). Signs and symptoms may occur from between 3 and 30 days following the tick bite. The care of pregnant patients with a tick bite or suspected Lyme disease should be managed similarly to non-pregnant adults, including the consideration of antibiotics for prophylaxis and treatment. The primary objective of this committee opinion is to inform practitioners about Lyme dis...
Publication date: Available online 30 May 2020Source: Comparative Immunology, Microbiology and Infectious DiseasesAuthor(s): Bijan Esmaeilnejad, Mousa Tavassoli, Bahram Dalir-Naghadeh, Awat Samiei, Sepideh Rajabi, Vahid Mohammadi, Ehsan Anassori, Shahin Ehteshamfar
Publication date: Available online 30 May 2020Source: EXPLOREAuthor(s): Lena Sagi-Dain, Shlomi Sagi
Authors: Tzikas S, Papadopoulos C, Evangeliou AP, Vassilikos V PMID: 32470561 [PubMed - as supplied by publisher]
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Authors: Park YG, Choi J, Seol JW Abstract During pregnancy, the uterus undergoes intense neovascularization and vascular remodeling to supply oxygen and nutrients to the embryo. During this period, progesterone secreted from the ovary has effects on vascular remodeling in the endometrium and interacts with angiogenic factors. However, the exact mechanism of uterine vascular remodeling during pregnancy is poorly understood. Therefore, the aim of the present study was to investigate the association between angiopoietin-2 (Ang-2), one of the angiopoietins, and intrauterine vessel remodeling during pregnancy, and to d...
Toronto doctors say they’re optimistic politicians are beginning to turn their attention to the spread of COVID-19 in working-class neighbourhoods full of essential workers, and that Ontario's new testing strategy could help tackle one of the virus' 'last bastions' in Canada.
At least in Canada and other western countries we know that our isolation will end eventually, in contrast to those displaced by conflict and living in camps and shelters around the world, writes Marwa Awad.
Publication date: Available online 29 May 2020Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Elisabetta Torlone, Camilla Festa, Gloria Formoso, Marina Scavini, Maria Angela Sculli, Elena Succurro, Laura Sciacca, Paolo Di Bartolo, Francesco Purrello, Annunziata Lapolla
Conclusion: These observations definitively demonstrate an important role of PFN1 in mediating cell-cell adhesion during the initial stage of embryo implantation and suggest a potential therapeutic target or novel biomarker for patients suffering from implantation failure. PMID: 32466630 [PubMed - as supplied by publisher]