MiR-379 relieves myocardial injury after acute myocardial infarction by regulating tumor necrosis factor- α-induced protein 8.

CONCLUSIONS: MiR-379 has a binding site with TNFAIP8 and can inhibit its activity by binding to TNFAIP8 mRNA. SiRNA-TNFAIP8 can inhibit the NF-κB signaling pathway and protect myocardial cells from AMI-induced myocardial damage by reducing the apoptosis level of myocardial cells. PMID: 32414226 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32414226?dopt=Abstract

Source: Panminerva Medica - May 17, 2020 Category: General Medicine Tags: Panminerva Med Source Type: research