Barrett ’s Epithelial Thickness, Assessed by Volumetric Laser Endomicroscopy, is Associated with Response to Radiofrequency Ablation

Radiofrequency ablation (RFA) is the most common treatment for flat Barrett ’s esophagus (BE), but reasons for varying outcomes are poorly understood. A recently developed contrast-enhancement algorithm allows reliable measurement of Barrett’s epithelial thickness (BET) from volumetric laser endomicroscopy (VLE) images and correlation with response to RFA. Using this al gorithm, we investigated whether patients with thicker Barrett’s mucosa are less likely to respond to RFA. In the future, this algorithm may guide choice of RFA dosing or endoscopic resection.

Source: Clinical Gastroenterology and Hepatology - May 15, 2020 Category: Gastroenterology Authors: Iris J.M. Levink, Guillermo J. Tearney, Nicole S. Erler, Herbert C. Wolfsen, Peter D. Siersema, Michael B. Wallace Source Type: research