Implementation of a Reference-Scaled Average Bioequivalence Approach for Highly Variable Acetylsalicylic Acid in Fixed-Dose Combination with Clopidogrel Versus Enteric Aspirin in Chinese Subjects Under Fasting Conditions: A Phase  1, Open-Label, Randomized, Crossover Study

ConclusionApplication of the reference-scaled average bioequivalence approach to evaluate bioequivalence of acetylsalicylic acid in Chinese male and female healthy volunteers under fasting conditions demonstrated bioequivalence of test and reference formulations.Trial RegistrationCTR20181695.
Source: Advances in Therapy - Category: Drugs & Pharmacology Source Type: research