Mesenchymal stem cell therapy of acute thermal burns: A systematic review of the effect on inflammation and wound healing

Publication date: Available online 15 May 2020Source: BurnsAuthor(s): Filip Rangatchew, Peter Vester-Glowinski, Bo Sonnich Rasmussen, Eva Haastrup, Lea Munthe-Fog, Maj-Lis Talman, Christian Bonde, Krzysztof T. Drzewiecki, Anne Fischer-Nielsen, Rikke Holmgaard
Source: Burns - Category: Dermatology Source Type: research

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In conclusion, sitting for prolonged periods of time without interruption is unfavorably associated with DBP and HDL cholesterol. Exercise Slows Inappropriate Growth of Blood Vessels in a Mouse Model of Macular Degeneration https://www.fightaging.org/archives/2020/07/exercise-slows-inappropriate-growth-of-blood-vessels-in-a-mouse-model-of-macular-degeneration/ Excessive growth of blood vessels beneath the retina is a proximate cause of blindness in conditions such as macular degeneration. Researchers here provide evidence for physical activity to be influential in the pace at which this process of tissue...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
In conclusion, the present findings confirmed an essential role of HOTAIR in the regulation of ESC proliferation and stemness. Therefore, targeting HOTAIR in ESCs may be a potentially promising therapy for burn wound healing. PMID: 32582996 [PubMed - as supplied by publisher]
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
CONCLUSIONS: In this series, the success rate of CCST after a mean observation period of 357 weeks was 65.1%, and preoperative epithelial defect was the most relevant risk factor. PMID: 32599277 [PubMed - as supplied by publisher]
Source: The Ocular Surface - Category: Opthalmology Authors: Tags: Ocul Surf Source Type: research
Publication date: Available online 20 June 2020Source: Wound MedicineAuthor(s): Sangeetha Palakkara, Swapan Kumar Maiti, Divya Mohan, Shivaraju S., Raguvaran R., Kalaiselvan E, Naveen Kumar
Source: Wound Medicine - Category: General Medicine Source Type: research
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
The skin, which serves as the first barrier of the human body, is particularly susceptible to exogenous injuries. Skin wounds, including acute burns and chronic non-healing ulcers, are commonly observed in cli...
Source: Stem Cell Research and Therapy - Category: Stem Cells Authors: Tags: Review Source Type: research
Publication date: Available online 4 June 2020Source: Stem Cell ReportsAuthor(s): Baskar Ramdas, Raghuveer Singh Mali, Lakshmi Reddy Palam, Ruchi Pandey, Zhigang Cai, Santhosh Kumar Pasupuleti, Sarah S. Burns, Reuben Kapur
Source: Stem Cell Reports - Category: Stem Cells Source Type: research
Publication date: Available online 22 May 2020Source: BurnsAuthor(s): Tuvshintugs Baljinnyam, Enkhtuya Radnaa, Niimi Yosuke, Satoshi Fukuda, Donald S. Prough, Perenlei Enkhbaatar
Source: Burns - Category: Dermatology Source Type: research
Abstract Drugs targeting chromatin-modifying enzymes have entered clinical trials for myeloid malignancies, including INCB059872, a selective irreversible inhibitor of Lysine-Specific Demethylase 1 (LSD1). While initial studies of LSD1 inhibitors suggested these compounds may be used to induce differentiation of acute myeloid leukemia (AML), the mechanisms underlying this effect and dose-limiting toxicities are not well understood. Here, we used precision nuclear run-on sequencing (PRO-seq) and ChIP-seq in AML cell lines to probe for the earliest regulatory events associated with INCB059872 treatment. The changes ...
Source: Gene - Category: Genetics & Stem Cells Authors: Tags: Gene Source Type: research
The currently used classification of eye burns was proposed in 1973 by N.A. Puchkovskaya and V.M. Nepomnyashaya. Recent emergence of the concept of limbal stem cells of the corneal epithelium and its application in clinical practice has significantly expan...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Burns, Electricity, Explosions, Fire, Scalds Source Type: news
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