The sodium channel Nav1.7 is involved in paclitaxel-induced peripheral neuropathy though ERK1/2 signaling in rats.

CONCLUSION: These results indicated that the sodium channel Nav1.7 in the DRG exerted an important function in paclitaxel-induced neuropathy, which was associated with ERK phosphorylation in neurons. PMID: 32407275 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32407275?dopt=Abstract

Source: Current Neurovascular Research - May 13, 2020 Category: Neurology Authors: Wang GJ, Zhang X, Huang LD, Xiao Y Tags: Curr Neurovasc Res Source Type: research