Absorption, metabolism and excretion of surufatinib in rats and humans.
CONCLUSION: Fecal excretion was the predominant way for the elimination of surufatinib and its metabolites in rats and humans. No disproportionate circulating metabolite was observed in humans.
PMID: 32407271 [PubMed - as supplied by publisher]
Source: Current Drug Metabolism - Category: Drugs & Pharmacology Authors: Li K, Ma S, Miao L, Fan S, Pan B, Zhang W, Su W, Xiong Y, Gu Z, Guo L, Sai Y Tags: Curr Drug Metab Source Type: research